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Tree peony bark, Paeonia × suffruticosa. Botanical plate: 047-Paeonia x suffruticosa
Plate: 047-Paeonia x suffruticosa. Abraham Jacobus Wendel. Public domain.

Tree peony bark

Paeonia × suffruticosa · 牡丹皮

Herbs & Roots. Chinese Medicine.

Also called Mu dan pi, Moutan bark, Moutan root bark, Tree peony root bark

Pinyin: Mǔ dān pí

Pregnancy caution; bleeding risk

The root bark of the tree peony, used in Chinese medicine to cool heat in the blood and ease painful, stuck blood.

Did you know? In China the tree peony is called the king of flowers, and the city of Luoyang has held peony festivals for centuries.

What it may help, and how strong the proof is

  • Inflammation. Lab and animal studies show anti-inflammatory activity, mainly from a chemical called paeonol. Human trials are lacking.
    Traditional proof
  • Women's health. Used in tradition for painful periods with stuck blood. No good human trials exist.
    Traditional proof
  • Skin. Used in tradition for rashes and red swellings. Lab studies only.
    Traditional proof

Parts of the body

Immune system, Joints, Hormones & reproduction, Skin & hair

Traditional use

Traditional Chinese Medicine has used peony bark for heat in the blood, such as nosebleeds, rashes and red swellings, and for painful periods with stuck blood. It appears in Dan Zhi Xiao Yao San and Qing Hao Bie Jia Tang.

How it is classified

Herbal actions
Anti-inflammatory, Circulatory, Antispasmodic. Energy: cooling.
Chinese medicine
牡丹皮 Clear heat. Nature: cool. Flavour: bitter, pungent. Enters the Heart, Liver and Kidney channels.

How people take it

Traditional doses are about 6 to 12 grams of dried root bark in a decoction. Human studies are few, so no proven dose exists.

Decoction and capsule.

Where to get it

A woody shrub grown in gardens and farms in China, Japan and Korea. The root bark is dried and sold as slices, capsules and extracts.

Be careful

Traditional texts advise caution in pregnancy because the bark can move blood. Paeonol slows platelets in lab studies, so bleeding risk may rise with blood thinners.

Avoid if: pregnancy; bleeding disorders; before surgery.

Mixing with other things

  • Works well together

    Dan Zhi Xiao Yao San (Moutan and Gardenia Free and Easy Wanderer) pairs them to clear heat and ease moods that feel stuck or irritable.

  • Works well together

    Qing Hao Bie Jia Tang (Artemisia and Turtle Shell Decoction) pairs them for long-lasting heat and fevers that come at night.

  • Works well together

    Also in Dan Zhi Xiao Yao San, where dong quai nourishes blood.

  • Works well together

    Qing Hao Bie Jia Tang (Artemisia and Turtle Shell Decoction) pairs them with rehmannia for lingering heat.

  • Use caution
    Blood thinners (warfarin, Eliquis, Xarelto, Plavix, daily aspirin)

    Lab studies show paeonol slows platelets. With blood thinners, bleeding risk may rise. Human data are lacking.

Adds up with others that may slow blood clotting: , , , , , , , , , , , , , and 40 more.

Found in these formulas

Six Flavor Rehmannia (TCM)

The honest take

Tree peony bark has a respected role in Chinese formulas, and lab work shows several active chemicals. Human trials are few, so claims for pain, skin or period problems are mostly traditional. Its effect on bleeding with blood thinners deserves care.