Herbs Hub
A drawing made for this site. Drag it to turn it.

MSM (methylsulfonylmethane)

Methylsulfonylmethane

Supplements. Modern nutrition.

Also called Dimethyl sulfone, Organic sulfur

Pinyin: jiǎ jī huáng xiān jiǎ wán

Spanish: MSM (metilsulfonilmetano)

Little long-term safety data

A sulfur compound sold as a supplement for joint pain and muscle soreness.

Did you know? MSM is a breakdown product of DMSO, a solvent used in labs and veterinary medicine.

What it may help, and how strong the proof is

  • Joint pain & arthritis. Small trials in knee osteoarthritis show modest pain relief for some people. Results are mixed and studies are short.
    Early proof
  • Muscles & exercise. Small studies test MSM for muscle soreness after exercise. Evidence is weak, so the claim is unproven.
    Traditional proof

Parts of the body

Joints, Muscles

Traditional use

MSM has no traditional herbal use. It became popular as a joint supplement in the 1990s.

How it is classified

Herbal actions
Anti-inflammatory, Analgesic. Energy: neutral.

How people take it

Joint studies used about 1 to 3 grams a day, often split into doses. Many joint products combine MSM with glucosamine.

Powder, capsule and tablet.

Where to get it

MSM is found in small amounts in milk, fruits, vegetables, tea and coffee. Supplements are made by a chemical process and sold as powders and capsules.

Be careful

MSM is usually well tolerated, with occasional gas, bloating or headache at higher doses. Long-term safety and safety in pregnancy have not been well studied. Check with a doctor before using it if you have a health condition or take other medicines.

Avoid if: pregnancy; breastfeeding.

Mixing with other things

  • Works well together

    Often sold together in joint blends. The combined benefit is not well proven.

The honest take

MSM has small, short trials for joint pain, and results are mixed. Its claim for muscle soreness is weak. Long-term safety data are limited, so it is best used with a doctor's guidance.